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NRAC controls CD36-mediated fatty acid uptake in adipocytes and lipid clearance in vivo
Inderjeet Singh, Yasuhiro Onogi, Filipe Menezes,
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Dina Khasanova, Lingru Kang, Chenxi Wang, Julio Ruiz-Trave, Sapna Sharma, Ahmed Khalil, Valentin K Reichenbach, Yingzi Shi, Andrew Flatley, Xiaocheng Yan, Andreas Israel, Nathalia R V Dragano, Juan Antonio Aguilar-Pimentel, Anne Hoffmann, Adhideb Ghosh, Falko Noé, Christian Wolfrum, Sebastian Cucuruz, Ann-Christine König, Ingo Burtscher, Stefanie M Hauck, Heiko Lickert, Susanna M Hofmann, Regina Feederle, Sonja C Schriever, Rene Hernandez-Bautista, Gencer Sancar, Alberto Cebrian-Serrano, Igor Tetko, Helmut Fuchs, Valérie Gailus-Durner, Matthias Blüher, Martin Hrabě de Angelis, and Siegfried Ussar
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sAPPα inhibits neurite outgrowth in primary mouse neurons via GABA B Receptor subunit 1a
Dylan Barber, Casandra Salinas-Salinas, Samah Houmam, Kriti Shukla, and Heather C. Rice
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Tumour initiated purinergic signalling promotes cardiomyocyte RBFOX1 degradation and cardiotoxicity from DNA damaging anticancer agents
Saymon Tejay, Maria Areli Lorenzana-Carrillo, Guocheng Huang,
+11 more authors
Seyed Amirhossein Tabatabaei Dakhili, Yuan -Yuan Zhao, Farah Eaton, Michelle Mendiola Pla, Dawn E. Bowles, Adam Kinnaird, D. Ian Paterson, Edith Pituskin, John R. Ussher, Evangelos D. Michelakis, and Gopinath Sutendra
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Extracellular Vesicles-Dependent Secretion Regulates Intracellular CYFIP2 Protein Homeostasis in Cortical Neurons
Michael J. Culp, Breandan J. Rosolia, Cameron Keyser, and Jingqi Yan
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Cardiac PAD2 expression and myocardial citrullination decline with age in female mice independent of estrogen
Samantha K. Shorthill, Finley R. Klinger, Aykhan Yusifov,
+8 more authors
Joshua P. Thornburg, Marjie P. Schmitt, Emma R. Mehl, Sharanya S. Bettadapura, Mason H. Agor, Florence Teulé-Finley, Brian D. Cherrington, and Danielle R. Bruns
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TMEM184B modulates endolysosomal acidification via the vesicular proton pump
Elizabeth B. Wright, Erik G. Larsen, Marco Padilla-Rodriguez, Paul R. Langlais, and Martha R. C. Bhattacharya
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Sex-dependent influence of LMAN1 on allergen-induced airway hyperresponsiveness
Lindsay G Swaby, Faith L Sauber, Madelyn H Miller,
+6 more authors
Mylena C Xavier, Wesley Lim, Peter Daniel Poulson, Xiang Zhu, Bin Zhang, and Justine T Tigno-Aranjuez
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Maternal 129S1/SvImJ background attenuates the placental phenotypes induced by chronic paternal alcohol exposure
Sanat S. Bhadsavle, Katherine Z. Scaturro, and Michael C. Golding
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Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues
Sanjiv Neupane, Daniel B. Williamson, Robyn A. Roth, Carmen M. Halabi, Robert S. Haltiwanger, and Bernadette C. Holdener
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FAM76B regulates PI3K/Akt/NF-κB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA
Juan Wang, Xinyue Zhao, Qizhi Wang,
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Xiaojing Zheng, Dilihumaer Simayi, Junli Zhao, Peiyan Yang, Qinwen Mao, and Haibin Xia
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Disruption of mitochondrial unfolded protein response results in telomere shortening in mouse oocytes and somatic cells
Mauro Cozzolino, Yagmur Ergun, Emma Ristori, Akanksha Garg, Gizem Imamoglu, and Emre Seli
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PXR Activation Relieves Deoxynivalenol‐Induced Liver Oxidative Stress Via Malat1 LncRNA m6A Demethylation
Yue Feng, Jiakun Shen, Zishen Lin, Zeyi Chen, Min Zhou, and Xi Ma
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Knockdown of ANGPTL2 promotes left ventricular systolic dysfunction by upregulation of NOX4 in mice
Pauline Labbé, Cécile Martel, Yan-Fen Shi,
+9 more authors
Augusto Montezano, Ying He, Marc-Antoine Gillis, Marie-Ève Higgins, Louis Villeneuve, Rhian Touyz, Jean-Claude Tardif, Nathalie Thorin-Trescases, and Eric Thorin
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SETD2 as an epigenetic sentinel of transcriptional fidelity in cardiomyocytes: a mechanistic link to heart failure
Jiang Chang, Weijia Luo, Zhishi Chen,
+10 more authors
Xin Yi, Yuan Dai, Wei Yu, Garrett Jensen, Zhongjing Wang, Xinjie Wang, Ye Tao, Xiao Du, Kenneth Ramos, and Keith Youker
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Knockout Mouse Studies Show Mitochondrial CLPP Peptidase and CLPX Unfoldase to Act in Matrix Condensates Near IMM, as Fast Stress Response in Protein Assemblies for Transcript Processing, Translation, and Heme Production
Jana Key, Suzana Gispert, and Georg Auburger
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Cardiac muscle–restricted partial loss of Nos1ap expression has limited but significant impact on electrocardiographic features
Alexa Smith, Dallas Auer, Morgan Johnson,
+5 more authors
Ernesto Sanchez, Holly Ross, Christopher Ward, Aravinda Chakravarti, and Ashish Kapoor
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Transmembrane protein 184B (TMEM184B) promotes expression of synaptic gene networks in the mouse hippocampus
Elizabeth B. Wright, Erik G. Larsen, Cecilia M. Coloma-Roessle, Hannah R. Hart, and Martha R.C. Bhattacharya
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GRAF1 Regulates Brown and Beige Adipose Differentiation and Function
Xue Bai, Qiang Zhu, Matthew Combs, Martin Wabitsch, Christopher P. Mack, and Joan M. Taylor
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Dominant CIZ1 fragments drive epigenetic instability and are expressed in early stage cancers
Gabrielle L. Turvey, Ernesto López de Alba, Emma Stewart,
+8 more authors
Lewis Byrom, Heather Cook, Sajad Sofi, Ahmad Alalti, Justin F-X Ainscough, Andrew Mason, Alfred A Antson, and Dawn Coverley
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Epigenetic instability caused by absence of CIZ1 drives transformation during quiescence cycles
Olivia G. Dobbs, Rosemary H. C. Wilson, Katherine Newling, Justin F.-X. Ainscough, and Dawn Coverley
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Mouse and human studies support DSTYK loss of function as a low-penetrance and variable expressivity risk factor for congenital urinary tract anomalies
Jeremiah Martino, Qingxue Liu, Katarina Vukojevic,
+28 more authors
Juntao Ke, Tze Y. Lim, Atlas Khan, Yask Gupta, Alejandra Perez, Zonghai Yan, Hila Milo Rasouly, Natalie Vena, Natalie Lippa, Jessica L. Giordano, Marijan Saraga, Mirna Saraga-Babic, Rik Westland, Monica Bodria, Giorgio Piaggio, Pavan K. Bendapudi, Alejandro D. Iglesias, Ronald J. Wapner, Velibor Tasic, Fan Wang, Iuliana Ionita-Laza, Gian Marco Ghiggeri, Krzysztof Kiryluk, Rosemary V. Sampogna, Cathy L. Mendelsohn, Vivette D. D’Agati, Ali G. Gharavi, and Simone Sanna-Cherchi
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Disruption of Mitochondrial Unfolded Protein Response Results in Telomere Shortening in Mouse Oocytes and Somatic Cells
Mauro Cozzolino, Yagmur Ergun, Emma Ristori, Akanksha Garg, Gizem Imamoglu, and Emre Seli
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Unraveling the role of Slc10a4 in auditory processing and sensory motor gating: implications for neuropsychiatric disorders?
Barbara Ciralli, Thawann Malfatti, Markus M. Hilscher,
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Richardson N. Leao, Christopher R. Cederroth, Katarina E. Leao, and Klas Kullander
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Six-Transmembrane Epithelial Antigen of Prostate 3 Promotes Hepatic Insulin Resistance and Steatosis
Ting Ding, Siping Chen, Wenchang Xiao,
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Zhen Liu, Jun Tu, Yongjie Yu, Bizhen Dong, Wenping Chen, and Yong Zeng
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Metabolic regulation of the proteasome under hypoxia by Poldip2 controls fibrotic signaling in vascular smooth muscle cells
Felipe Paredes, Holly C. Williams, Izabela Suster,
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Macarena Tejos, Roberto Fuentealba, Bethany Bogan, Claire M. Holden, and Alejandra San Martin
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Inhibition of 2-arachidonoylglycerol degradation enhances glial immunity by single-cell transcriptomic analysis
Dexiao Zhu, Jian Zhang, Jack Hashem, Fei Gao, and Chu Chen
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SIM2s directed Parkin-mediated mitophagy promotes mammary epithelial cell differentiation
Lilia Sanchez, Jessica Epps, Steven Wall,
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Cole McQueen, Scott J. Pearson, Kelly Scribner, Elizabeth A. Wellberg, Erin D. Giles, Monique Rijnkels, and Weston W. Porter
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A novel role for endoplasmic reticulum protein 46 (ERp46) in platelet function and arterial thrombosis in mice
Junsong Zhou, Yi Wu, Lubica Rauova,
+9 more authors
Gavin Koma, Lu Wang, Mortimer Poncz, Hong Li, Tong Liu, Karen P. Fong, Joel S. Bennett, Satya P. Kunapuli, and David W. Essex
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PBAF chromatin remodeler complexes that mediate meiotic transitions in mouse
Rodrigo O. de Castro, Luciana Previato de Almeida, Agustin Carbajal, Irma Gryniuk, and Roberto J. Pezza
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TBC1Domain Family Member 25 deficiency aggravates cerebral ischemia‐reperfusion injury via TAK1‐JNK/p38 pathway
Zongyong Zhang, Tengfei Ma, Zhengyi Fu,
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Yu Feng, Zhen Wang, Song Tian, Zhen Liu, Wei Wei, Xiang Li, Jincao Chen, and Wenyuan Zhao
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Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice
Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks,
+7 more authors
Chitvan Mittal, Elena Alina Demeter, Sophie Nelissen, Jennifer K. Grenier, Ann E. Tate, Faraz Ahmed, and Scott A. Coonrod
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Growth arrest of PPP2R5C and PPP2R5D double knockout mice indicates a genetic interaction and conserved function for these PP2A B subunits
Jade J. Dyson, Fatima Abbasi, Prajakta Varadkar, and Brent McCright
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TRIM35-mediated degradation of nuclear PKM2 destabilizes GATA4/6 and induces P53 in cardiomyocytes to promote heart failure
Maria Areli Lorenzana-Carrillo, Keshav Gopal, Nikole J. Byrne,
+12 more authors
Saymon Tejay, Bruno Saleme, Subhash K. Das, Yongneng Zhang, Alois Haromy, Farah Eaton, Michelle Mendiola Pla, Dawn E. Bowles, Jason R. B. Dyck, John R. Ussher, Evangelos D. Michelakis, and Gopinath Sutendra
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Loss of C2 Domain Protein (C2CD5) Alters Hypothalamic Mitochondrial Trafficking, Structure, and Function
Chaitanya K. Gavini, Chelsea R. White, Virginie Mansuy-Aubert, and Gregory Aubert
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CUX2 deficiency causes facilitation of excitatory synaptic transmission onto hippocampus and increased seizure susceptibility to kainate
Toshimitsu Suzuki, Tetsuya Tatsukawa, Genki Sudo,
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Caroline Delandre, Yun Jin Pai, Hiroyuki Miyamoto, Matthieu Raveau, Atsushi Shimohata, Iori Ohmori, Shin-ichiro Hamano, Kazuhiro Haginoya, Mitsugu Uematsu, Yukitoshi Takahashi, Masafumi Morimoto, Shinji Fujimoto, Hitoshi Osaka, Hirokazu Oguni, Makiko Osawa, Atsushi Ishii, Shinichi Hirose, Sunao Kaneko, Yushi Inoue, Adrian Walton Moore, and Kazuhiro Yamakawa
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Extracellular S100B inhibits A‐type voltage‐gated potassium currents and increases L‐type voltage‐gated calcium channel activity in dopaminergic neurons
Eric A. Bancroft, Martha De La Mora, Gauri Pandey, Sara M. Zarate, and Rahul Srinivasan
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Prion-like domains drive CIZ1 assembly formation at the inactive X chromosome
Sajad Sofi, Louisa Williamson, Gabrielle L. Turvey,
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Charlotte Scoynes, Claire Hirst, Jonathan Godwin, Neil Brockdorff, Justin Ainscough, and Dawn Coverley
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NRF2-Dependent Placental Effects Vary by Sex and Dose following Gestational Exposure to Ultrafine Particles
Jonathan C. Behlen, Carmen H. Lau, Drew Pendleton,
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Yixin Li, Aline Rodrigues Hoffmann, Michael C. Golding, Renyi Zhang, and Natalie M. Johnson
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Enhancing endocannabinoid signalling in astrocytes promotes recovery from traumatic brain injury
Mei Hu, Dexiao Zhu, Jian Zhang,
+6 more authors
Fei Gao, Jack Hashem, Philip Kingsley, Lawrence J Marnett, Ken Mackie, and Chu Chen
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Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice
Kelly L. Sams, Chinatsu Mukai, Brooke A. Marks,
+7 more authors
Chitvan Mittal, Elena Alina Demeter, Sophie Nelissen, Jennifer K. Grenier, Ann E. Tate, Faraz Ahmed, and Scott A. Coonrod
