Publications Using TIGM Mice
Folate regulation of axonal regeneration in the rodent central nervous system through DNA methylation. Iskandar BJ, Rizk E, Meier B, Hariharan N, Bottiglieri T, Finnell RH, Jarrard DF, Banerjee RV, Skene JH, Nelson A, Patel N, Gherasim C, Simon K, Cook TD, Hogan KJ. J Clin Invest. 2010 May 3;120(5):1603-16.
Also see commentary:
Neuronal injury: folate to the rescue? Kronenberg G, Endres M.I. J Clin Invest. 2010 May 3;120(5):1383-6.
DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke W. Tu, X. Xu, L. Peng, X. Zhong, W. Zhang, M. Soundarapandian, C. Balel, M. Wang, N. Jia, W. Zhang, et al. Cell, 2010 Jan 22; 140(2): 222-234.
Regulation of succinate dehydrogenase activity by SIRT3 in mammalian mitochondria. Cimen H, Han MJ, Yang Y, Tong Q, Koc H, Koc EC. Biochemistry. 2010 Jan 19;49(2):304-11.
NAD<+>-dependent deacetylase SIRT3 regulates mitochondrial protein synthesis by deacetylation of the ribosomal protein MRPL10. Yang Y, Cimen H, Han MJ, Shi T, Deng JH, Koc H, Palacios OM, Montier L, Bai Y, Tong Q, Koc EC. J Biol Chem. 2009 Dec 30.
TRPM1 is required for the depolarizing light response in retinal ON-bipolar cells. Morgans CW, Zhang J, Jeffrey BG, Nelson SM, Burke NS, Duvoisin RM, Brown RL.Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19174-8.
Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Chang M, Jin W, Sun SC.Nat Immunol. 2009 Oct;10(10):1089-95.
The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Gray RS, Abitua PB, Wlodarczyk BJ, Szabo-Rogers HL, Blanchard O, Lee I, Weiss GS, Liu KJ, Marcotte EM, Wallingford JB, Finnell RH. Nat Cell Biol. 2009 Oct;11(10):1225-32.
MsrB1 (methionine-R-sulfoxide reductase 1) knock-out mice: roles of MsrB1 in redox regulation and identification of a novel selenoprotein form. Fomenko DE, Novoselov SV, Natarajan SK, Lee BC, Koc A, Carlson BA, Lee TH, Kim HY, Hatfield DL, Gladyshev VN. J Biol Chem. 2009 Feb 27;284(9):5986-93.
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.Jakubowski H, Perla-Kaján J, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM. FASEB J. 2009 Jun;23(6):1721-7.
Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice.Jakubowski H, Perla-Kaján J, Finnell RH, Cabrera RM, Wang H, Gupta S, Kruger WD, Kraus JP, Shih DM. FASEB J. 2009 Jun;23(6):1721-7.
Publication describing our library and technology
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, Markesich DC, Burnett MB, Zhu Q, Dionne KM, Richter LJ, Finnell RH, Sands AT, Zambrowicz BP, Abuin A.Genome Res. 2008 Oct;18(10):1670-9.
